The Cannabidiol industry commonly referred to as CBD is flourishing, conservatively projected to hit $16 billion in the United States by 2025. According to a survey conducted by the Brightfield Group of 5,000 people, a cannabis market research firm More than 60% of CBD users have taken it for anxiety. While these many people use cannabidiol to release pain, more scientific research is required to be certain it is reliable.
To subdue the stigma associated with cannabidiol oil, deep analysis is required.
In this article, we will try to answer all of your queries, how and whether CBD oil works and how it can be used to relieve chronic pain.
The journal Cannabis and Cannabinoid Research published a report, according to that report the use of cannabis for pain relief dates back to ancient China.
Among the most prevailed components of the active ingredients of cannabis, CBD is ranked second. Cannabinoids are found in various plants, but usually, it is linked with cannabis. CBD is extracted directly from the hemp plant; it is an essential component of medical marijuana. It does not cause a “high.” even though CBD is a component of marijuana by itself, and here is why?
Endocannabinoid receptors of the brain are affected when it produces a “high” feeling as Tetrahydrocannabinol enters the human body. This results in creating pleasure chemicals such as dopamine in the brain.
Because CBD does not affect the same receptors as tetrahydrocannabinol, CBD does not produce a euphoric “high” or psychoactive impact. These impacts are commonly found in other cannabinoids, such as tetrahydrocannabinol (THC).
Among the treatments for chronic pain, CBD is relatively new and understudied. According to various studies, CBD can be helpful in reducing inflammation and fighting anxiety, which are often associated with chronic pain.
Institute of Medicine of The National Academies reported that more than 100 million Americans are suffering from chronic pain. Cannabidiol oil has steadily obtained popularity among many people experiencing chronic pain as a natural method of pain relief. Increment in healthcare costs and harm productivity at work is very much possible as the quality of the ride is decreasing drastically.
The precise method of how CBD oil might relieve the pain is still under study. However, the evidence suggests that Cannabidiol does improve the body system by contributing in improving human health and brain functions such as memory, mood, as the endocannabinoid system influences how we experience pain.
So far, the evidence of CBD effects on pain management is usually from animal-based research.
Most of these studies are to determine whether CBD oil helps in the treatment of diseases chronic pain, depression, anxiety, and other chronically debilitating and degenerative conditions.
Cannabidiol is a substance found in the marijuana plant, it is sometimes promoted as a natural remedy to pain medication in the treatment of arthritis, back pain and of common conditions.
CBD oil is proven very efficient in reducing inflammation to help reduce chronic pain. Effects of chronic pain such as sleep disruption are also treated by CBD oil which promotes sounder and better sleep. This eventually reduces the usage of opioids significantly, which was widely consumed by the people to treat patients of chronic pain and sleep ammonia.
To receive and translate signals from cannabinoids, humans have an endocannabinoid system. We can say, the endocannabinoid system (ECS) is a cell signaling system. Some cannabinoids are also produced by this system as well, these cannabinoids are called endocannabinoids. The endocannabinoid system is responsible for regulating sleep, immune-system responses, pain, and other some functions.
The interaction of CBD with the core component of endocannabinoid receptors in your brain and the immune system is also pointed out by various researchers. Receptors are tiny proteins attached to cells; they help cells respond by receiving (mostly chemical) signals from different stimuli.
Anti-inflammatory and pain-relieving effects are created by this response to help with pain management. This clearly indicates that CBD oil with other products can benefit people suffering from any type of chronic pain.
CBD oil proved its effectiveness in treating pain as well as the substance is widely stated with a minimum to no side effects. Co-director of McMaster University’s Michael G. DeGroote Center for Medicinal Cannabis Research, James MacKillop said, “It’s promising in a lot of different therapeutic avenues because it is relatively safe”.
To investigate the population private pain management center initially recruited 131 patients as an initial sample.
After CBD rich hemp was added into their regiment, over half of chronic pain patients get down or even eliminated their opioids in less than 8 weeks. Add more than 94% of CBD users reported improvement in the quality of their life.
Moreover, the European journal of pains conducted a study on the animal model to see if CBD can help people manage their pain. A topical gel containing CBD was applied on rats of 4 days, the gel was proven very successful in reducing arthritis pain of animals.
Furthermore, in this report CBD oil was tested against chronic pain as well. Covering dozens of trials, researchers compare the result of multiple systematic reviews assessing how well CBD works to relieve chronic pain. According to their research for chronic pain, there is substantial evidence that CBD is an effective treatment.
Another study conducted by Journal Experimental Medicine also confirms these results. The study reported that CBD can reduce pain and inflammation significantly and efficiently.
According to the research published in Tirupati X and clinical risk management, People suffering from conditions such as multiple sclerosis and cancer also reported that cannabinoid can be helpful in reducing pain greatly.
Various other studies also prove the positive effects of people taking the CBD to elevate their fibromyalgia pain. Some of these patients may experience few side effects, such as dry mouth and dizziness after using this chemical compound.
One 2018 review assessed how well CBD works to relieve chronic pain. The review looked at studies conducted between 1975 and March 2018. These studies examined various types of pain, including:
- cancer pain
- neuropathic pain
- fibromyalgia
Based on these studies, researchers concluded that CBD was effective in overall pain management and didn’t cause negative side effects.
A 2016 studyTrusted Source looked at CBD use in rats with arthritis.
Researchers applied CBD gel to rats for four days in a row. The rats received either 0.6, 3.1, 6.2, or 62.3 milligrams (mg) per day. The researchers noted reduced inflammation and overall pain in the rats’ affected joints. There were no obvious side effects.
Rats who received low doses of 0.6 or 3.1 mg didn’t improve their pain scores. The researchers found that 6.2 mg/day was a high enough dose to reduce the rats’ pain and swelling.
In addition, rats who received 62.3 mg/day had similar outcomes to the rats that received 6.2 mg/day. Receiving a substantially larger dosage didn’t result in them having less pain.
The anti-inflammatory and pain-relieving effects of CBD gel could potentially help people with arthritis. However, more human studies are needed.
Based on the above-mentioned studies we can easily say that the researchers are confident that the CBD oil can be proven effective in pain management and it has no adverse side effects.
Sources:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851925/
https://www.ncbi.nlm.nih.gov/books/NBK425767/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371734/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2503660/
https://www.tandfonline.com/doi/full/10.1080/00325481.2019.1685298
https://doi.org/10.3389/fphar.2018.01259\
https://www.nytimes.com/2019/10/16/style/self-care/cbd-oil-benefits.html
Hill KP, Palastro MD, Johnson B, Ditre JW. Cannabis and Pain: A Clinical Review. Cannabis Cannabinoid Res. 2017;2(1):96-104. DOI:10.1089/can.2017.0017
Shannon S, Lewis N, Lee H, Hughes S. Cannabidiol in Anxiety and Sleep: A Large Case Series. Perm J. 2019;23:18-41. DOI:10.7812/TPP/18-041
Institute of Medicine. Relieving Pain in America: A Blueprint for Transforming Prevention, Care, Education, and Research. Washington, DC: The National Academies Press; 2011. DOI:10.17226/13172
Philpott HT, OʼBrien M, McDougall JJ. Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis.
